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「"Gray DHD "[Author]」の検索結果

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Ubiquitination of MHC Class II Is Required for Development of Regulatory but Not Conventional CD4 T Cells.

MCL-1 is essential for survival but dispensable for metabolic fitness of FOXP3 regulatory T cells.

Dual targeting of CDK4/6 and BCL2 pathways augments tumor response in estrogen receptor positive breast cancer.

Deep profiling of apoptotic pathways with mass cytometry identifies a synergistic drug combination for killing myeloma cells.

Deletion of self-reactive CCR7- thymocytes in the absence of MHC expression on thymic epithelial cells.

PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia.

A phase 1b dose-escalation and expansion study of the BCL-2 inhibitor venetoclax combined with tamoxifen in ER and BCL-2-positive metastatic breast cancer.

Acquisition of the recurrent Gly101Val mutation in BCL2 confers resistance to venetoclax in patients with progressive chronic lymphocytic leukemia.

The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation.

VDAC2 enables BAX to mediate apoptosis and limit tumor development.

Dynamic molecular monitoring reveals that SWI-SNF mutations mediate resistance to ibrutinib plus venetoclax in mantle cell lymphoma.

How do thymic epithelial cells die?

Thymospheres Are Formed by Mesenchymal Cells with the Potential to Generate Adipocytes, but Not Epithelial Cells.

A critical epithelial survival axis regulated by MCL-1 maintains thymic function in mice.

Combined immune checkpoint blockade as a therapeutic strategy for BRCA1-mutated breast cancer.

Cell death and thymic tolerance.

Isolation of thymic epithelial cells and analysis by flow cytometry.

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