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Augmentation of Positive Valence System-Focused Cognitive Behavioral Therapy by Inaudible High-Frequency Sounds for Anhedonia: A Trial Protocol for a Pilot Study.

著者 Ito M , Miyamae M , Yokoyama C , Yamashita Y , Ueno O , Maruo K , Komazawa A , Niwa M , Honda M , Horikoshi M
JAMA Netw Open.2019 Nov 01 ; 2(11):e1915819.
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Recent conceptualizations in Research Domain Criteria have indicated that anhedonia, 1 of 2 core symptoms of depression, which can be treatment resistant, is associated with deficits in the positive valence system, and inaudible high-frequency sound therapy has been shown to enhance reward-related brain circuitry. Hence, cognitive behavioral therapy focusing on the positive valence system enhanced with sound therapy could have a synergistic effect on anhedonia.
PMID: 31747035 [PubMed - in process]
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