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A Double-Blind Placebo-Controlled Trial of Omega-3 Fatty Acids as a Monotherapy for Adolescent Depression.

著者 Gabbay V , Freed RD , Alonso CM , Senger S , Stadterman J , Davison BA , Klein RG
J Clin Psychiatry.2018 Jun 26 ; 79(4):.
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Reports are mixed on the efficacy of omega-3 fatty acids (O3FA) for the treatment of major depressive disorder (MDD), with only limited data in adolescents. The present trial aimed to investigate systematically the efficacy of O3FA as a monotherapy, compared to a placebo, in adolescents with MDD. Secondarily, we explored O3FA effects on anhedonia, irritability, and suicidality-all key features of adolescent MDD.
PMID: 29985566 [PubMed - in process]
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