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Insulin-like growth factor 2 mRNA-binding protein 3 is a novel post-transcriptional regulator of Ewing sarcoma malignancy.

著者 Mancarella C , Pasello M , Ventura S , Grilli A , Calzolari L , Toracchio L , Lollini PL , Donati DM , Picci P , Ferrari S , Scotlandi K
Clin Cancer Res.2018 Apr 27 ; ():.
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Large-scale sequencing studies have indicated that besides genomic alterations, the post-transcriptional regulation of gene expression or epigenetic mechanisms largely influences the clinical behavior of Ewing sarcoma (ES). We investigated the significance of the RNA-binding protein IGF2BP3 in the regulation of ES aggressiveness.
PMID: 29703820 [PubMed - as supplied by publisher]
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