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Internal tissue references for 18Fluorodeoxyglucose vascular inflammation imaging: Implications for cardiovascular risk stratification and clinical trials.

著者 Ahlman MA , Vigneault DM , Sandfort V , Maass-Moreno R , Dave J , Sadek A , Mallek MB , Selwaness MAF , Herscovitch P , Mehta NN , Bluemke DA
PLoS One.2017 ; 12(11):e0187995.
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18Fluorodeoxyglucose (FDG) positron emission tomography (PET) uptake in the artery wall correlates with active inflammation. However, in part due to the low spatial resolution of PET, variation in the apparent arterial wall signal may be influenced by variation in blood FDG activity that cannot be fully corrected for using typical normalization strategies. The purpose of this study was to evaluate the ability of the current common methods to normalize for blood activity and to investigate alternative methods for more accurate quantification of vascular inflammation.
PMID: 29131857 [PubMed - in process]
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