絞り込み

16314

広告

アジア各地に邦楽の公演可能なライブホール開設を発表

大手音楽会社のソニー・ミュージックエンタテインメントとそのグループ会社は、官民ファンドの支援を受けて、アジア各地に日本のアーティストなどが公演を行えるライブホー...

  1. ヒートショックプロテインを増やす入浴法 ...
  2. 痛風対策してますか?食事・運動・サプリメ...
  3. 英エコノミスト誌が予測「日本は人口減少で...
  4. 高浜原発4号機 燃料入れる作業始まる 来...

ニュース一覧

Cytoprotective effects of dietary flavonoids against cadmium-induced toxicity.

著者 Li X , Jiang X , Sun J , Zhu C , Li X , Tian L , Liu L , Bai W
Ann N Y Acad Sci.2017 Apr 19 ; ():.
この記事をPubMed上で見るPubMedで表示
この記事をGoogle翻訳上で見る Google翻訳で開く

スターを付ける スターを付ける     (20view , 0users)
  • このエントリーをはてなブックマークに追加

Full Text Sources

Cadmium (Cd) damages the liver, kidney, bones, reproductive system, and other organs. Flavonoids, such as anthocyanins and flavonols, which are commonly found in plant foods, have shown protective effects against Cd-induced damage. The cytoprotective effects of flavonoids against Cd-induced diseases are mainly attributable to three mechanisms. First, flavonoids clear reactive oxygen species, thereby reducing lipid peroxide production and improving the activity of antioxidation enzymes. Second, flavonoids chelate Cd, thus reducing the accumulation of Cd and altering the levels of other essential metal ions in vivo. Third, flavonoids reduce DNA damage and inhibit apoptosis. In addition, flavonoids were found to inhibit inflammation and fibrosis and improve glycometabolism and the secretion of reproductive hormones. We introduce the daily dosage and absorption rate of flavonoids and then focus on their bioactive effects against Cd-induced toxicity and reveal the underlying metabolic pathway, which provides a basis for further study of the nutritional prevention of Cd-induced injury. In particular, a better understanding is needed of the structure-activity relationship of flavonoids against Cd toxicity, which has not yet been reported.
PMID: 28423468 [PubMed - as supplied by publisher]
印刷用ページを開く Endnote用テキストダウンロード