絞り込み

16406

広告

原子炉建屋想定し高専生技術競う (デイリースポーツ)

東京電力福島第1原発の原子炉建屋を想定した会場で、高専生が自作ロボットの操作技術を競う「廃炉創造ロボコン」が16日、福島県楢葉町で開かれた。廃炉技術に興味を持っ...

  1. [企業] Andreessen Horo...
  2. 金井さん、17日宇宙へ (デイリースポー...
  3. 宇宙飛行士の金井さん あす打ち上げ 長期...
  4. [企業] Relay社 蛋白質の動きの理...

ニュース一覧

The domestic dog is becoming an increasingly valuable model species in medical genetics, showing particular promise to advance our understanding of cancer and orthopaedic disease. Here we undertake the largest canine genome-wide association study to date, with a panel of over 4,200 dogs genotyped at 180,000 markers, to accelerate mapping efforts. For complex diseases, we identify loci significantly associated with hip dysplasia, elbow dysplasia, idiopathic epilepsy, lymphoma, mast cell tumour and granulomatous colitis; for morphological traits, we report three novel quantitative trait loci that influence body size and one that influences fur length and shedding. Using simulation studies, we show that modestly larger sample sizes and denser marker sets will be sufficient to identify most moderate- to large-effect complex disease loci. This proposed design will enable efficient mapping of canine complex diseases, most of which have human homologues, using far fewer samples than required in human studies.
PMID: 26795439 [PubMed - in process]
印刷用ページを開く Endnote用テキストダウンロード