絞り込み

16545

広告

辺野古承認撤回 県が審査請求弁明書を国交相に送付 (毎日新聞)

[PR] 沖縄県は19日、米軍普天間飛行場(宜野湾市)の名護市辺野古移設を巡り、辺野古沿岸部の埋め立て承認を撤回した県への対抗措置として、政府が行った行政不服審...

  1. 免疫受容体CD300fの機能促進で偽アレ...
  2. 伊勢谷友介と森星のデートをNEWSポスト...
  3. 韓中首脳「朝鮮半島問題、解決の機が熟しつ...
  4. 2025年万博 今週開催地が決定 大阪府...

ニュース一覧

Plasmonic Nanodiamonds: Targeted Core-Shell Type Nanoparticles for Cancer Cell Thermoablation.

著者 Rehor I , Lee KL , Chen K , Hajek M , Havlik J , Lokajova J , Masat M , Slegerova J , Shukla S , Heidari H , Bals S , Steinmetz NF , Cigler P
Adv Healthc Mater.2014 Oct 21 ; ():.
この記事をPubMed上で見るPubMedで表示
この記事をGoogle翻訳上で見る Google翻訳で開く

スターを付ける スターを付ける     (249view , 0users)

Full Text Sources

Miscellaneous

Targeted biocompatible nanostructures with controlled plasmonic and morphological parameters are promising materials for cancer treatment based on selective thermal ablation of cells. Here, core-shell plasmonic nanodiamonds consisting of a silica-encapsulated diamond nanocrystal coated in a gold shell are designed and synthesized. The architecture of particles is analyzed and confirmed in detail using electron tomography. The particles are biocompatibilized using a PEG polymer terminated with bioorthogonally reactive alkyne groups. Azide-modified transferrin is attached to these particles, and their high colloidal stability and successful targeting to cancer cells overexpressing the transferrin receptor are demonstrated. The particles are nontoxic to the cells and they are readily internalized upon binding to the transferrin receptor. The high plasmonic cross section of the particles in the near-infrared region is utilized to quantitatively ablate the cancer cells with a short, one-minute irradiation by a pulse 750-nm laser.
PMID: 25336437 [PubMed - as supplied by publisher]
印刷用ページを開く Endnote用テキストダウンロード