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Genetic Alterations Associated With Progression From Pancreatic Intraepithelial Neoplasia to Invasive Pancreatic Tumor.

著者 Murphy SJ , Hart SN , Lima JF , Kipp BR , Klebig M , Winters JL , Szabo C , Zhang L , Eckloff BW , Petersen GM , Scherer SE , Gibbs RA , McWilliams RR , Vasmatzis G , Couch FJ
Gastroenterology.2013 Aug 1 ; ():.
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Department of Molecular Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA. Electronic address: murphy.stephen@mayo.edu.

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Increasing grade of pancreatic intraepithelial neoplasia (PanIN) has been associated with progression to pancreatic ductal adenocarcinoma (PDAC). However, the mechanisms that control progression from PanINs to PDAC are not well understood. We investigated the genetic alterations involved in this process.
PMID: 23912084 [PubMed - as supplied by publisher]
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