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Thrombin-activatable fibrinolysis inhibitor is associated with severity and outcome of severe meningococcal infection in children.

著者 Emonts M , de Bruijne EL , Guimarães AH , Declerck PJ , Leebeek FW , de Maat MP , Rijken DC , Hazelzet JA , Gils A
J Thromb Haemost.2008 Feb ; 6(2):268-76.
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Department of Pediatrics, Erasmus MC-Sophia, Rotterdam, The Netherlands.

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In pediatric meningococcal sepsis, an imbalance between coagulation and fibrinolysis and proinflammatory action play major roles. We hypothesized that thrombin activatable fibrinolysis inhibitor (TAFI) and/or TAFI activation markers are involved in the pathogenesis of meningococcal sepsis.
PMID: 18021301 [PubMed - indexed for MEDLINE]
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