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Transverse relaxation rates of pulmonary dissolved-phase Hyperpolarized Xe as a biomarker of lung injury in idiopathic pulmonary fibrosis.

著者 Kammerman J , Hahn AD , Cadman RV , Malkus A , Mummy D , Fain SB
Magn Reson Med.2020 Mar 11 ; ():.
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The MR properties (chemical shifts and decay rates) of dissolved-phase hyperpolarized (HP) Xe are confounded by the large magnetic field inhomogeneity present in the lung. This work improves measurements of these properties using a model-based image reconstruction to characterize the decay rates of dissolved-phase HP Xe in healthy subjects and patients with idiopathic pulmonary fibrosis (IPF).
PMID: 32162357 [PubMed - as supplied by publisher]
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