To investigate the clinical features of patients with atrial fibrillation (AF) and occult pulmonary embolism (PE). Clinical data of 67 AF patients complicated with PE (AP group) admitted to the Tianjin Chest hospital from January 2014 to July 2018 were analyzed. A total of 70 AF patients without PE served as the control group (AF group). The AP group was divided into 2 subgroups: AF with occult PE (OPE subgroup) and symptomatic PE (SPE subgroup). The clinical features of OPE subgroup were analyzed. The levels of leukocyte counts, C-reactive protein, D-dimer and N-terminal pro-brain natriuretic peptide in the AP group were (7.4±2.7)×10(9)/L, 18.0 (5.9, 65.7) mg/L, 2.61 (1.63, 3.72) mg/L and 1 657 (600, 3 172)ng/L, which were higher than those in the AF group (0.008, 0.001, 0.001 and 0.002, respectively); Arterial oxygen pressure in the AP group was (74±13) mmHg (1 mmHg=0.133 kPa), lower than the AF group (0.001); and pulmonary artery systolic pressure was (46±16) mmHg, higher than the AF group (0.001). In the OPE subgroup, 12 cases (66.7%) were complicated with localized pulmonary embolism, more than those in the SPE subgroup (0.008), and pulmonary artery systolic pressure was (39±11) mmHg, which was lower than the SPE subgroup (0.001); the levels of leukocyte counts, C-reactive protein and D-dimer in the OPE subgroup were (7.6±2.3)×10(9)/L, 18.3 (3.7, 67.3) mg/L and 2.31 (1.27, 3.61) mg/L, higher than the AF group (all 0.05); arterial oxygen pressure in the OPE subgroup was (75±12) mmHg, lower than the AF group (0.05). Occult pulmonary embolism is not uncommon in patients with atrial fibrillation. Comparing with AF group, the OPE subgroup was associated with increased levels of inflammatory markers and D-dimer and hypoxemia.
PMID: 31505721 [PubMed - in process]