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D-dimer levels during and after anticoagulation withdrawal in patients with venous thromboembolism treated with non-vitamin K anticoagulants.

著者 Legnani C , Martinelli I , Palareti G , Ciavarella A , Poli D , Ageno W , Testa S , Mastroiacovo D , Ciammaichella M , Bucherini E , Mumoli N , Cosmi B
PLoS One.2019 ; 14(7):e0219751.
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D-dimer levels measured during and after vitamin K antagonist withdrawal may be used in clinical practice to assess the individual risk of recurrent venous thromboembolism. Currently, direct oral anticoagulants (DOACs) are frequently used in venous thromboembolism treatment; however, their pharmacokinetics and pharmacodynamics characteristics are completely different than vitamin K antagonists. The present study aimed at comparing the results of D-dimer levels during and after anticoagulation withdrawal in patients with venous thromboembolism treated with DOACs or warfarin.
PMID: 31310608 [PubMed - in process]
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