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Nanochitosan antimicrobial activity against Streptococcus mutans and Candida albicans dual-species biofilms.

著者 Ikono R , Vibriani A , Wibowo I , Saputro KE , Muliawan W , Bachtiar BM , Mardliyati E , Bachtiar EW , Rochman NT , Kagami H , Xianqi L , Nagamura-Inoue T , Tojo A
BMC Res Notes.2019 Jul 08 ; 12(1):383.
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Chitosan nanoparticle (nanochitosan) has a broad antimicrobial spectrum against diverse pathogenic microorganisms. However, its effect on dental caries-associated microorganisms, such as Streptococcus mutans and Candida albicans is yet to be explored. These microorganisms are known for causing early childhood caries. Therefore, this study was aimed at investigating nanochitosan inhibition capacity against dual-species biofilms of S. mutans and C. albicans. In this study, nanochitosan antimicrobial activity is reported against mono and dual biofilm species of S. mutans and/or C. albicans at 3 and 18 h incubation time. Nanochitosan inhibition capacity was observed through biofilm mass quantity and cell viability.
PMID: 31287001 [PubMed - in process]
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