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Continuous Versus Intermittent Vancomycin Infusions in Infants: A Randomized Controlled Trial.

著者 Gwee A , Cranswick N , McMullan B , Perkins E , Bolisetty S , Gardiner K , Daley A , Ward M , Chiletti R , Donath S , Hunt R , Curtis N
Pediatrics.2019 Jan 30 ; ():.
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In adults, continuous infusions of vancomycin (CIV) are associated with earlier attainment of target drug concentrations, require fewer blood samples for monitoring, and may reduce drug toxicity. We aimed to determine, in young infants, if CIV or intermittent infusions of vancomycin (IIV) better achieves target vancomycin concentrations at the first steady-state level and to compare the frequency of drug-related adverse effects.
PMID: 30700564 [PubMed - as supplied by publisher]
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