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Response to therapeutic monoclonal antibodies for multiple myeloma in African Americans versus whites.

著者 Chehab S , Zhang C , Panjic EH , Chen Z , Kaufman JL , Lonial S , Nooka A , Harvey RD
Cancer.2018 Oct 10 ; ():.
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Myeloma occurs disproportionately in African Americans, with disparities in outcomes potentially caused by access to care, cytogenetics, and immunity. A gap in knowledge of immune function dissimilarities between African Americans and whites exists. Data for other diseases suggest innate differences in immunity and inflammatory markers, with potential implications for therapeutic monoclonal antibodies reliant on secondary immune activation for activity.
PMID: 30303526 [PubMed - as supplied by publisher]
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