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Determinants of adherence and consequences of the transition from adolescence to adulthood among young people with severe haemophilia (TRANSHEMO): study protocol for a multicentric French national observational cross-sectional study.

著者 Resseguier N , Rosso-Delsemme N , Beltran Anzola A , Baumstarck K , Milien V , Ardillon L , Bayart S , Berger C , Bertrand MA , Biron-Andreani C , Borel-Derlon A , Castet S , Chamouni P , Claeyssens Donadel S , De Raucourt E , Desprez D , Falaise C , Frot
BMJ Open.2018 Jul 25 ; 8(7):e022409.
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Severe haemophilia is a rare disease characterised by spontaneous bleeding from early childhood, which may lead to various complications, especially in joints. It is nowadays possible to avoid these complications thanks to substitutive therapies for which the issue of adherence is major. The transition from adolescence to adulthood in young people with severe haemophilia is a critical period as it is associated with a high risk of lack of adherence to healthcare, which might have serious consequences on daily activities and on quality of life.
PMID: 30049701 [PubMed - in process]
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