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Multiple HBV transfusion transmissions from undetected occult infections: revising the minimal infectious dose.

著者 Candotti D , Assennato SM , Laperche S , Allain JP , Levicnik-Stezinar S
Gut.2018 Jun 29 ; ():.
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HBV infection by blood components is currently prevented in most developed countries by combining sensitive HBV surface antigen (HBsAg) assays, nucleic acid testing (NAT) and in a few of them antibodies against the HBV core antigen (anti-HBc) screening. HBV transmissions by blood components from three repeat donors tested negative for HBsAg and HBV DNA with a highly sensitive screening test (limit of detection (LOD): 3.4 IU/mL) were investigated.
PMID: 29959168 [PubMed - as supplied by publisher]
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