絞り込み

16545

広告

辺野古承認撤回 県が審査請求弁明書を国交相に送付 (毎日新聞)

[PR] 沖縄県は19日、米軍普天間飛行場(宜野湾市)の名護市辺野古移設を巡り、辺野古沿岸部の埋め立て承認を撤回した県への対抗措置として、政府が行った行政不服審...

  1. 免疫受容体CD300fの機能促進で偽アレ...
  2. 伊勢谷友介と森星のデートをNEWSポスト...
  3. 韓中首脳「朝鮮半島問題、解決の機が熟しつ...
  4. 2025年万博 今週開催地が決定 大阪府...

ニュース一覧

Identification of Rice Extract Components that Increase β-Glucocerebrosidase Levels in Human Epidermal Keratinocytes.

著者 Maeda K , Ogino Y , Nakamura A , Nakata K , Kitagawa M , Ito S
Foods.2018 Jun 18 ; 7(6):.
この記事をPubMed上で見るPubMedで表示
この記事をGoogle翻訳上で見る Google翻訳で開く

スターを付ける スターを付ける     (55view , 0users)

Full Text Sources

Miscellaneous

Rice miso contains many ingredients derived from rice and has been a valuable source of nutrition since ancient times. We found that the consumption of rice miso led to improvements in the moisture content of cheek stratum corneum, skin viscoelasticity, and skin texture. Further, rice miso extract was found to increase the mRNA expression and activity of β-glucocerebrosidase (β-GCase), an enzyme involved in ceramide synthesis in the stratum corneum, in cultures. In this study, we identified the lipid-derived components of rice that increase the β-GCase activity in cultured human epidermal keratinocytes. The methanol fraction of rice extract induced an increase in the mRNA expression and activity of β-GCase in keratinocytes. The active fraction of rice was found to contain phosphatidic acid (PA) and lysophosphatidic acid (LPA). The total PA concentration in rice was 973.9 ng/mg dry weight, which was 17.5 times higher than that in steamed rice. Among the molecular species, PA_18:2/18:2 was the most frequently found. The total LPA concentration in rice was 29.6 ng/mg dry weight, and 2-LPA_18:2 was the most frequently found LPA. Since PA and LPA increase the mRNA expression and activity of β-GCase in keratinocytes, they are thought to be the active ingredients in rice that increase the β-GCase levels in human epidermal keratinocytes.
PMID: 29912147 [PubMed]
印刷用ページを開く Endnote用テキストダウンロード