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Neural Responsiveness to Reward as an Index of Depressive Symptom Change Following Cognitive-Behavioral Therapy and SSRI Treatment.

著者 Burkhouse KL , Gorka SM , Klumpp H , Kennedy AE , Karich S , Francis J , Ajilore O , Craske MG , Langenecker SA , Shankman SA , Hajcak G , Phan KL
J Clin Psychiatry.2018 Jun 12 ; 79(4):.
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Reward positivity (RewP), a neurophysiologic index of reward responsivity, is consistently reduced in participants with depression and, to a lesser extent, anxiety. It remains unknown, however, whether RewP can be altered as psychiatric symptoms change with treatment. The current study addressed this question by examining differences in RewP within patients before and after 12 weeks of treatment with a selective serotonin reuptake inhibitor (SSRI) or cognitive-behavioral therapy (CBT). We also examined the utility of RewP as a predictor of symptom change during CBT and SSRI treatment.
PMID: 29894598 [PubMed - in process]
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