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A study on indices of apixaban anticoagulation: A single-center prospective study.

著者 Komiyama M , Miyazaki Y , Wada H , Iguchi M , Abe M , Ogawa H , Akao M , Yamakage H , Satoh-Asahara N , Sunagawa Y , Morimoto T , Hasegawa K
J Pharmacol Sci.2018 May 16 ; ():.
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Depending on the characteristics of patients, the blood concentration of apixaban can unexpectedly increase, possibly leading to bleeding events. Anti-FXa activity reflects the apixaban blood concentration; however, measurement of this activity is both time-consuming and expensive. The current study aimed to evaluate the usefulness of routinely measured coagulation indices as future indicators of the efficacy and safety of apixaban.
PMID: 29866521 [PubMed - as supplied by publisher]
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