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The activity and role of autophagy in the pathogenesis of diabetic nephropathy.

著者 Liu WJ , Huang WF , Ye L , Chen RH , Yang C , Wu HL , Pan QJ , Liu HF
Eur Rev Med Pharmacol Sci.2018 May ; 22(10):3182-3189.
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Evidence suggested that deficiency of autophagy is involved in the pathogenesis of diabetic nephropathy (DN). However, some recent studies have also shown that autophagy is activated in renal cells under diabetic conditions. In this review, we discuss whether autophagy is inactivated in renal cells in DN as well as the therapeutic potential of autophagy for treating DN, in order to aid future investigation in this field.
PMID: 29863264 [PubMed - in process]
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