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Gut microbiota metabolites, amino acid metabolites and improvements in insulin sensitivity and glucose metabolism: the POUNDS Lost trial.

著者 Heianza Y , Sun D , Li X , DiDonato JA , Bray GA , Sacks FM , Qi L
Gut.2018 Jun 02 ; ():.
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Alterations in gut microbiota have been linked to host insulin resistance, diabetes and impaired amino acid metabolism. We investigated whether changes in gut microbiota-dependent metabolite of trimethylamine N-oxide (TMAO) and its nutrient precursors (choline and L-carnitine) were associated with improvements in glucose metabolism and diabetes-related amino acids in a weight-loss diet intervention.
PMID: 29860242 [PubMed - as supplied by publisher]
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