[Action of amsidine on the evolution of lymphocyte cultures and on the structure of human metaphase chromosomes].

PMID:2957038
Turchini MF , Mathe O , Marques-Verdier A , Chassagne J , Perissel B , Bastide P , Malet P , Turchini JP
Comptes rendus des séances de la Société de biologie et de ses filiales
Chromosomic alterations can be observed after the effect of a antimitotic amsidine on metaphases of cultured human lymphocytes: gaps, breaks, exchange figures, deletions, rings. Moreover we notice, among these cells, particular lines of big sized lymphoplasmocytoid cells, whose rate is abnormally high when compared to reference cultures.


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