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Impact of broad regulatory regions on Gdf5 expression and function in knee development and susceptibility to osteoarthritis.

著者 Pregizer SK , Kiapour AM , Young M , Chen H , Schoor M , Liu Z , Cao J , Rosen V , Capellini TD
Ann Rheum Dis.2018 Jan 08 ; ():.
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Given the role of growth and differentiation factor 5 (GDF5) in knee development and osteoarthritis risk, we sought to characterise knee defects resulting from Gdf5 loss of function and how its regulatory regions control knee formation and morphology.
PMID: 29311146 [PubMed - as supplied by publisher]
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