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不安払しょく 被ばく量試算できるアプリ開発へ (NHK)

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2017 EULAR recommendations for a core data set to support observational research and clinical care in rheumatoid arthritis.

著者 Radner H , Chatzidionysiou K , Nikiphorou E , Gossec L , Hyrich KL , Zabalan C , van Eijk-Hustings Y , Williamson PR , Balanescu A , Burmester GR , Carmona L , Dougados M , Finckh A , Haugeberg G , Hetland ML , Oliver S , Porter D , Raza K , Ryan P , Sant
Ann Rheum Dis.2018 Jan 04 ; ():.
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Personalised medicine, new discoveries and studies on rare exposures or outcomes require large samples that are increasingly difficult for any single investigator to obtain. Collaborative work is limited by heterogeneities, both what is being collected and how it is defined. To develop a core set for data collection in rheumatoid arthritis (RA) research which (1) allows harmonisation of data collection in future observational studies, (2) acts as a common data model against which existing databases can be mapped and (3) serves as a template for standardised data collection in routine clinical practice to support generation of research-quality data. A multistep, international multistakeholder consensus process was carried out involving voting via online surveys and two face-to-face meetings. A core set of 21 items ('what to collect') and their instruments ('how to collect') was agreed: age, gender, disease duration, diagnosis of RA, body mass index, smoking, swollen/tender joints, patient/evaluator global, pain, quality of life, function, composite scores, acute phase reactants, serology, structural damage, treatment and comorbidities. The core set should facilitate collaborative research, allow for comparisons across studies and harmonise future data from clinical practice via electronic medical record systems.
PMID: 29301783 [PubMed - as supplied by publisher]
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