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Stratification of knee osteoarthritis: two major patient subgroups identified by genome-wide expression analysis of articular cartilage.

著者 Soul J , Dunn SL , Anand S , Serracino-Inglott F , Schwartz JM , Boot-Handford RP , Hardingham TE
Ann Rheum Dis.2017 Dec 22 ; ():.
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Osteoarthritis (OA) is a heterogeneous and complex disease. We have used a network biology approach based on genome-wide analysis of gene expression in OA knee cartilage to seek evidence for pathogenic mechanisms that may distinguish different patient subgroups.
PMID: 29273645 [PubMed - as supplied by publisher]
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