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A polymorphic MYC response element in KBTBD11 influences colorectal cancer risk, especially in interaction with a MYC regulated SNP rs6983267.

著者 Gong J , Tian J , Lou J , Wang X , Ke J , Li J , Yang Y , Gong Y , Zhu Y , Zou D , Peng X , Yang N , Mei S , Zhong R , Chang J , Miao X
Ann Oncol.2017 Dec 18 ; ():.
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MYC is a well-established cancer driver gene regulating the expression of numerous genes, indicating that polymorphisms in MYC response elements could affect tumorigenesis through altering MYC regulation. We performed integrative multistage study to evaluate the effects of variants in MYC response elements and colorectal cancer (CRC) risk.
PMID: 29267898 [PubMed - as supplied by publisher]
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