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Differential preventive activity of sulindac and atorvastatin in Apc(+/Min-FCCC)mice with or without colorectal adenomas.

著者 Chang WL , Jackson C , Riel S , Cooper HS , Devarajan K , Hensley HH , Zhou Y , Vanderveer LA , Nguyen MT , Clapper ML
Gut.2017 Nov 09 ; ():.
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The response of subjects to preventive intervention is heterogeneous. The goal of this study was to determine if the efficacy of a chemopreventive agent differs in non-tumour-bearing animals versus those with colorectal tumours. Sulindac and/or atorvastatin was administered to Apc(+/Min-FCCC) mice with known tumour-bearing status at treatment initiation.
PMID: 29122850 [PubMed - as supplied by publisher]
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