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Mucosa-associated invariant T cells link intestinal immunity with antibacterial immune defects in alcoholic liver disease.

著者 Riva A , Patel V , Kurioka A , Jeffery HC , Wright G , Tarff S , Shawcross D , Ryan JM , Evans A , Azarian S , Bajaj JS , Fagan A , Patel V , Mehta K , Lopez C , Simonova M , Katzarov K , Hadzhiolova T , Pavlova S , Wendon JA , Htun Oo Y , Klenerman P , W
Gut.2017 Nov 02 ; ():.
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Intestinal permeability with systemic distribution of bacterial products are central in the immunopathogenesis of alcoholic liver disease (ALD), yet links with intestinal immunity remain elusive. Mucosa-associated invariant T cells (MAIT) are found in liver, blood and intestinal mucosa and are a key component of antibacterial host defences. Their role in ALD is unknown.
PMID: 29097439 [PubMed - as supplied by publisher]
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