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In vitro effects of Apixaban on 5 different cancer cell lines.

著者 Guasti L , Squizzato A , Moretto P , Vigetti D , Ageno W , Dentali F , Maresca AM , Campiotti L , Grandi AM , Passi A
PLoS One.2017 ; 12(10):e0185035.
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Cancer is associated with hypercoagulability. However, several data suggest that anticoagulant drugs may have an effect on tumor development and progression mediated by both coagulation dependent processes and non-coagulation dependent processes. Therefore, we investigated the in vitro effects of Apixaban on cell proliferation, mortality, cell migration, gene expression and matrix metalloproteinase in 5 different cancer cell lines.
PMID: 29023465 [PubMed - in process]
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