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The effects of vildagliptin compared with metformin on vascular endothelial function and metabolic parameters: a randomized, controlled trial (Sapporo Athero-Incretin Study 3).

著者 Kitao N , Miyoshi H , Furumoto T , Ono K , Nomoto H , Miya A , Yamamoto C , Inoue A , Tsuchida K , Manda N , Kurihara Y , Aoki S , Nakamura A , Atsumi T ,
Cardiovasc Diabetol.2017 Oct 10 ; 16(1):125.
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Dipeptidyl peptidase-4 (DPP-4) inhibitors may have protective effects in the early stage of atherosclerosis in patients with type 2 diabetes, although similar effects in advanced atherosclerosis were not shown in recent randomized placebo-controlled studies. Therefore, we investigated the efficacy of DPP-4 inhibitor on endothelial function and glycemic metabolism compared with high-dose metformin.
PMID: 29017497 [PubMed - in process]
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