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Association of cervical precancer with human papillomavirus types other than 16 among HIV co-infected women.

著者 Massad LS , Xie X , Burk RD , D'Souza G , Darragh TM , Minkoff H , Colie C , Burian P , Palefsky J , Atrio J , Strickler HD
Am J Obstet Gynecol.2015 Sep 30 ; ():.
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HIV seropositive women face high risk for infection with oncogenic types of human papillomaviruses (oncHPV), abnormal Pap tests and precancer, but cervical cancer risk is only modestly increased. HPV16 is highly oncogenic but only weakly associated with HIV-status and immunosuppression, suggesting HPV16 may have a greater innate ability to evade host immune surveillance than other oncHPV types which in turn should result in a greater relative increase in the prevalence of other oncHPV types among women with cervical precancer.
PMID: 26433170 [PubMed - as supplied by publisher]
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