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Dissociable effects of mGluR5 allosteric modulation on distinct forms of impulsivity in rats: interaction with NMDA receptor antagonism.

著者 Isherwood SN , Pekcec A , Nicholson JR , Robbins TW , Dalley JW
Psychopharmacology (Berl).2015 Jun 12 ; ():.
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Impaired N-methyl-D-aspartate (NMDA) receptor signalling underlies several psychiatric disorders that express high levels of impulsivity. Although synergistic interactions exist between NMDA receptors and metabotropic glutamate receptor 5 (mGluR5), the significance of this interaction for impulsivity is unknown.
PMID: 26063678 [PubMed - as supplied by publisher]
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