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Changing pattern of femoral fractures in osteogenesis imperfecta with prolonged use of bisphosphonates.

著者 Nicolaou N , Agrawal Y , Padman M , Fernandes JA , Bell MJ
J Child Orthop.2012 Mar ; 6(1):21-7.
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Department of Orthopaedics, Sheffield Children's Hospital, Western Bank, Sheffield, South Yorkshire UK.

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Osteogenesis imperfecta (OI) has been treated with bisphosphonates for many years, with some clear clinical benefits. In adults, there are reports of a new pattern of atraumatic subtrochanteric fractures with bisphosphonate treatment. This study assesses if bisphosphonate treatment leads to an altered pattern of femoral fractures.
PMID: 23450103 [PubMed - in process]
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