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The RosR transcription factor is required for gene expression dynamics in response to extreme oxidative stress in a hypersaline-adapted archaeon.

著者 Sharma K , Gillum N , Boyd JL , Schmid A
BMC Genomics.2012 Jul 30 ; 13():351.
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Previous work has shown that the hypersaline-adapted archaeon, Halobacterium salinarum NRC-1, is highly resistant to oxidative stress caused by exposure to hydrogen peroxide, UV, and gamma radiation. Dynamic alteration of the gene regulatory network (GRN) has been implicated in such resistance. However, the molecular functions of transcription regulatory proteins involved in this response remain unknown.
PMID: 22846541 [PubMed - indexed for MEDLINE]
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