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アカウミガメ 人工繁殖で3世代目が誕生 和歌山 串本町 (NHK)

アカウミガメの繁殖に取り組んでいる和歌山県串本町の水族館で、人が飼育する環境で3世代目の繁殖に成功しました。水族館によりますと世界で初めてだということです。 串...

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ニュース一覧

Evolution of thrombin formation and fibrinolysis markers, including thrombin-activatable fibrinolysis inhibitor, during severe meningococcemia.

著者 Fouassier M , Moreau D , Thiollière F , Frère C , Marquès-Verdier A , Souweine B
Pathophysiol Haemost Thromb.2005 ; 34(6):284-7.
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A 17-year-old girl presented with Neisseria meningitidis sepsis, with evidence of disseminated intravascular coagulation. Substitution therapy with both antithrombin and protein C concentrates was initiated, leading to clinical and biological improvement. Sequential dosages were performed for biological markers including thrombin-activatable fibrinolysis inhibitor (TAFI). Substitution therapy with both antithrombin and protein C concentrates led to a clinical and biological improvement. Biological markers showed a decrease in thrombin generation and in plasminogen activator inhibitor 1 (PAI-1) and a return of TAFI to a normal value. Discontinuation of substitutive treatment was marked by a clinical relapse at 24 h, with thrombin generation and increase in PAI-1, while TAFI remained unchanged. This report shows the evolution of hemostasis markers during septic shock and provides new data concerning the effects of a substitutive therapy.
PMID: 16772741 [PubMed - indexed for MEDLINE]
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